TIG = Tijdschrift voor Integrale Geneeskunde

BESTEL TIG

T: 035 - 698 2250
BoekenService

TIG 18(2)4 E Vis-Renia

NavLeft

Abonneer

NavUp

Reageer

NavRight

Samenvatting
E Vis-Renia    Echinacea purpurea/angustifolia (2)

Aan vrijwel geen enkele andere plant schrijft men met zoveel kracht en overtuiging weer-standsverhogende kwaliteiten toe als aan Echinacea.. Zodra het najaar in aantocht is, vliegen de vele Echinacea producten als warme broodjes over de toonbank. Echinacea in huis hebben, staat ongeveer gelijk aan een herfst of winter zonder griep, verkoudheid of bronchitis. De vraag is echter of dit vertrouwen terecht is? Verhogen Echinacea producten werkelijk de weerstand en is het zinvol deze producten toe te passen bij al die lastige najaarskwalen?
In dit 2-delige artikel gaat Ellen Vis uitgebreid in op de therapeutische mogelijkheden die deze plant biedt. In het eerste deel belichtte zij reeds de herkomst van verschillende Echinacea soorten als ook het traditionele gebruik van de plant. Verder gaf zij een zeer complete en overzichtelijke weergave van de belangrijkste werkzame bestanddelen. In dit tweede deel beschrijft de auteur het werkingsmechanisme, de farmacologische eigenschappen en de verrichte wetenschappelijke studies. Zij completeert dit artikel met een praktische opsomming van indicaties en contra-indicaties. Bovendien geeft zij aan welke interacties en bijwerkingen mogelijk zijn. Ter afsluiting brengt Ellen Vis de advies-dosering en behandelduur onder de aandacht.

Summary
E Vis-Renia    Echinacea purpurea/angustifolia (2)

American Indians used Echinacea more than any other plant in the treatment of illness and injury. They used the roots of Echinacea angustifolia externally for the healing of wounds, burns, abscesses and insect bites and internally for infections, toothache and joint pains and as an antidote for rattlesnake bites. The Eclectics, a group of practitioners who were prominent around in the late 19th and early 20th centuries in the United States, adopted the use of Echinacea. Despite the opposition of conservative physicians, Echinacea angustifolia was included in the National Formulary and remained there until 1950. Although the interest had decreased in America after the discovery of modern antibi-otics, European physicians continued research. In Germany Maudaus demonstrated clearly the immune enhancing effects of a preparation made from the juice of the aerial parts of Echinacea purpurea. Around 1980 Echinacea preparations were rediscovered and became again immensly popular in America and Europe. Internally they are mainly used as supportive therapy for colds and chronic infections of the respiratory tract and the lower urinary tract. Locally they can be applied to poorly healing wounds and chronic ulcerations.
Analysis of Echinacea species has yielded an impressing assortment of chemical constitu-ents with pharmacological activities. The broad chemical composition of its com-pounds suggests synergistic and complemen-tary effects. Investigators proved that no single compound is responsible for the immunosti-mulating activity. They showed that especially polysaccharides (such as echinacoside), caffeic acid derivatives, alkylamides and glycoproteins are important compounds. Echinacea affects the immune system in a non-specific way. Research has indicated that the active compounds stimulate the alternate complement pathway which helps activate general immune cells to scavenge for bacteria and cellular debris. Echinacea alsö increases the levels of properidin, a serum protein that stimulates the alternate complement pathway. Many components have antibacterial, antivi-ral, antifungal, antiinflammatory, antihyaluro-nidase and wound-healing activities. Investigators proved that the polysaccharides enhance macrophage phagocytosis and stimulate them to produce a number of immune-potentiating compounds like TNE, interferon and interleukine 1. The monographs of the WHO and Commission E recommend the administration of Echinacea purpurea herb and Echinacea angustifolia root extracts as a supportive therapy for colds and infections of the respiratory and urinary tract. Oral administration of Echinacea preparations is not lower urinary tractrecommended during pregnancy and breastfeeding. Caution is advised for transplant patients taking immunosuppresive drugs. Side effects are generally not expected for oral or topical administration. Contact dermatitis may occur rarely in susceptible persons. There is no evidence that long-term usage will have any adverse effect or is detrimental on the immune function.

Keywords
Echinacea purpurea herba Echinacea angustifolia radix standardized extracts immunostimulating effects colds, chronic infections respiratory tract lower urinary tract

de Auteur
E Vis-Renia

NavLeft

Abonneer

NavUp

Reageer

NavRight

[Welkom] [Stichting TIG] [Bestel] [Archief] [Jaargangen 1 - 5] [Jaargangen 6 - 10] [Jaargangen 11- 15] [Jaargangen 16 - 20] [Jaarboeken 21 - 25] [Jaarboeken 26 -]